Clinical Science

Building clinical evidence is a key component of our initiative to improve patient outcomes with patient-friendly wireless cardiovascular solutions. A sample of Corventis clinical programs targeting future applications include:

MUSIC

The Multi-Sensor Monitoring in Congestive Heart Failure (MUSIC) Study is a prospective, multi-center, non-randomized study in 543 heart failure patients to develop and validate an algorithm to detect impending clinical events of acute heart failure decompensation.

• Anand IS, Greenberg BH, Fogoros RN, Fowler MB, Libbus I, Katra RP. Design of the Multi-Sensor Monitoring in Congestive Heart Failure (MUSIC) study: Prospective trial to assess the utility of continuous wireless physiological monitoring in heart failure. J Cardiac Fail 2011;17(1):11-16
• MUSIC clinical trial summary can be found at www.ClinicalTrials.gov (NCT00557804)

FARM

The Fluid Removal During Adherent Renal Monitoring (FARM) Study is a prospective, multi-center, non-randomized study in 25 hemodialysis patients designed to correlate measurements of fluid status with fluid output.

• Anand IS, Toth JA, Geyen KJ, Ma KW, Otterness S, Libbus I. Wireless monitoring of body fluid changes during hemodialysis: Results from the Fluid Removal During Adherent Renal Monitoring (FARM) study [abstract]. Circulation 2009; 120:S882-3
• FARM clinical trial summary can be found at www.ClinicalTrials.gov (NCT00919438)

ACUTE

The Adherent Monitoring of Congestive Heart Failure during Therapy for Excess Fluid (ACUTE) Study is a prospective, multi-center, non-randomized study in 60 acute decompensated heart failure patients in a combined inpatient and outpatient setting to assess the ability of physiological monitoring to prospectively identify patients at risk for heart failure readmission.

• ACUTE clinical trial summary can be found at www.ClinicalTrials.gov (NCT00919828)